Dr. Tamagnan is an Associate Professor Adjunct, Department of Psychiatry, and the CEO of XingImaging and Research Scientist at Xuanwu Hospital in Beijing. Dr. Tamagnan provides leadership and expert knowledge to colleagues to design and coordinate experiments for radiolabeling the tracers and for developing them into a radiopharmaceutical suitable for human administration. He is also responsible of the IND submission and working with the clinical team to validate the radiopharmaceutical. He has over 20 years of industrial and academic experience in the research and development of radiopharmaceuticals labeled with short-lived gamma-emitting radionuclides. Dr. Tamagnan is an active member of the nuclear medicine research community over the past 20 years and has been involved in the evaluation of over 70 CNS PET and SPECT imaging agents in human aimed at the development of improved diagnosis and treatment of neurologic and psychiatric conditions. He is a physician sponsor of over 35 INDs.
Dr. Gu has over 15 years of experience in clinical studies on early prediction and management of Parkinson's disease. She worked as project manager for multiple national and international cooperation projects, including MJFF projects, and played an important role in the setup and management for the first clinical center and specialist training system on Parkinson’s disease & Movement disorders in China. In 2018, Dr. Gu joined XingImaging China, started to build up the National PET network in China, and set up the standardized SOP for clinical operations for PET studies. In 2018, Dr. Gu joined XingImaging China, started to build up the National PET network in China, and set up the standardized SOP for clinical operations for PET studies.
In June 2019, Rebecca took on the role of COO after serving as a consultant for XingImaging since its inception. Prior to that she worked for more than 15 years with XingImaging’s principals at Molecular NeuroImaging (MNI) and the Institute for Neurodegenerative Disorders (IND). During her time at MNI and IND Rebecca helped build the companies’ regulatory affairs and quality groups, writing policies and procedures, developing structure with business awareness and regulatory rigor. During the second half of her career with these organizations, she headed up operations which expanded her experience to contract and budget review, company system oversight, business development, and employment management. She is a licensed attorney in the State of Connecticut focusing her part-time private practice on regulatory, trusts and estates, administrative and contract law.
Mr. Miluzzo joined XingImaging in June 2022 with over 25 years of business and Information Technology experience in the Life Sciences and Healthcare industries. In his career, John has led small and large-scale IT organizations, and successfully delivered numerous global IT transformation and modernization programs. John's expertise is in modernizing IT organizations, IT strategic planning, business digital transformation, and lab automation, with significant experience in mergers & acquisitions. He holds a BS in Computer Science from Gwynedd Mercy University and an MS in Technology Management from the University of Pennsylvania's Engineering and Wharton Business Schools.
George was trained as a radiochemist from Beijing Normal University and received a PhD. During this period, he was co-trained at the departments of Radiology and Pharmacology in the University of Pennsylvania. for two years. Then he worked as a postdoctoral researcher at Xuanwu Hospital Capital Medical University, during which he received training on GMP production of radiopharmaceutical at Molecular NeuroImaging, LLC (MNI). His research focuses on the development and transformation of radiopharmaceuticals. He has prepared and evaluated a number of compounds with novel structures and participated in the development of the BNU-F2 radiopharmaceutical synthesizer. He has also participated in the clinical transformation of new PET imaging tracers in China, including clinical research in hospitals and IND application, counting the β-amyloid tracer 18F-Florbetapir, vesicles monoamine transporter II imaging agent 18F-FP-DTBZ. He has extensive knowledge of about the regulations and production process of radiopharmaceuticals. Currently, he is mainly engaged in the development, production and laboratory management of PET imaging tracers.
Piu (Bill) Chan, M.D. Ph.D.
Dr. Chan is well known for his translational research on neurodegenerative disorders and other age-related disorders. Collaborating with Dr. Carlie Tanner on several unique cohorts, they were the first reporting that environmental exposures are the major risk factors for Parkinson’s disease. He has worked on developing models for CNS diseases including non-human primate models of Parkinson’s disease and dyskinesia. He has been studying familial and susceptibility genes and a variety of biomarkers for Parkinson's and Alzheimer's diseases in a few unique cohorts in China aimed for prediction and prevention of neurodegenerative diseases. Dr. Chan is the committee member for the MDS “Task Force on the definition of Parkinson’s disease” and “Telemedicine Task Force”. Dr. Chan’s team has participated in the International LRRK2 Consortium and Apple’s mPower projects. Dr. Chan has published more than 240 SCI peer-reviewed papers and about 350 peer-reviewed Chinese papers and served as editorial members of more than 15 international and Chinese journals.
Kenneth Marek, M.D.
Dr. Marek is a neurologist with widespread expertise in neurodegenerative disorders. He is internationally recognized as an expert in imaging of neurodegenerative disorders and has made significant contributions to early detection and diagnostic use of radiotracers for these disorders for PD, AD, HD and other disorders. He has developed novel clinical design for brain imaging studies and has been the Principal Investigator in several multicenter trials including PPMI and PARS.
John Seibyl, M.D.
Dr. Seibyl is an international expert on PET and SPECT imaging for neurodegenerative disorders. He is past President of the Brain Imaging Council of the Society of Nuclear Medicine. Dr. Seibyl is dually-boarded in Nuclear Medicine and Psychiatry and has twenty years of experience in clinical studies. He has made significant contributions to development of visual and quantitative analysis for PET imaging in neurodegenerative and neuropsychiatric disorders. Along with Dr. Marek he has directed and continues to direct several international multicenter imaging studies. Dr. Seibyl is an author on over one hundred publications on CNS imaging.
Olivier Barret, Ph.D.
Olivier Barret, Ph.D. has over ten years of experience of PET and SPECT image acquisition, correction and reconstruction as well as image processing and quantification as a kinetic modeler. He has investigated and validated many new radiopharmaceuticals for brain imaging both in non-human primates and humans, and has led many early phase projects using imaging to evaluate novel drugs. Dr. Barret oversees and coordinates the image acquisition, processing and analysis for the early tracer studies conducted at MNI.
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